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Nitrogen mustard compounds

Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Keyword Search:
76 – 90 of 173 results
76

Medchemexpress LLC 2-phenylaminoadenosine | 53296-10-9 | MFCD00055119 | 98.0% | 358.35 g/mol | C16H18N6O4 | 5 MG
SDP

CV1808 (2-phenylaminoadenosine) is a research-grade, non-selective A2 adenosine receptor agonist used in pharmacology and receptor-binding studies. It shows reported Ki values of 76 nM at the A2A receptor and 1,450 nM at the A3 receptor, has molecular formula C16H18N6O4 and molecular weight 358.35 g/mol, and is supplied as a solid with analytical purity around 98.0% for research use only.

  • Non-selective A2 adenosine receptor agonist
  • Reported Ki: A2A = 76 nM; A3 = 1,450 nM
  • Molecular formula C16H18N6O4; molecular weight 358.35 g/mol
  • Analytical purity approximately 98.0%
  • Supplied as a solid for laboratory research applications

ENCOMPASS_PREFERRED
77

Chemscene ChemScene | 6-Bromopyrazolo[1,5-a]pyrimidine | 10G | CS-M2471 | 0.98 | 705263-10-1| MFCD09832894 | 198.023
SDP

ChemScene | 6-Bromopyrazolo[1,5-a]pyrimidine | 10G | CS-M2471 | 0.98 | 705263-10-1| MFCD09832894 | 198.023

ENCOMPASS_PREFERRED
78

Chemscene (4-Aminobutyl)dimethylamine 25g
SDP

(4-Aminobutyl)dimethylamine 25g

ENCOMPASS_PREFERRED
79

STA PHARMACEUTICAL US LLC 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 10 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N

3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O

ENCOMPASS
80

Medchemexpress LLC Bis(2-chloroethyl)amine hydrochloride | 821-48-7 | MFCD00012515 | 98.0% | 178.49 g·mol⁻¹ | C4H10Cl3N | 100g
SDP

Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research

ENCOMPASS_PREFERRED
81

Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | C25H23F3N4O4S | 5 MG
SDP

ZL0580 is a BRD4 BD1-binding small molecule that induces epigenetic suppression of HIV by inhibiting Tat transactivation and transcription elongation and by promoting a repressive chromatin structure at the HIV promoter. It is supplied as a high-purity solid or as DMSO solutions for research applications and is stable under recommended storage conditions.

ENCOMPASS_PREFERRED
82

Medchemexpress LLC Camonsertib | 2417489-10-0 | 99.99% | 410.47 | 50 MG
SDP

Camonsertib is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. It demonstrates 30-fold selectivity for ATR over mTOR and over 2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases, exhibiting potent antitumor activity.

  • Orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM.
  • Demonstrates 30-fold selectivity for ATR over mTOR.
  • Exhibits potent antitumor activity.
  • Inhibits CHK1(Ser345) phosphorylation in LoVo cells.
  • Produces dose-dependent tumor growth inhibition in xenografts.
  • Shows greater anti-tumor effects in combination with PARPi Olaparib.

ENCOMPASS_PREFERRED
83

Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 10 MG
SDP

2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. The compound is identified by CAS 17378-30-2 and is characterized by the molecular formula C4H9Cl2O3P and a molecular weight of 206.99 g/mol (manufacturer datasheet).

  • Used as a building block or intermediate in organic synthesis.
  • Organophosphorus chemical class with a phosphoryl functionality.
  • CAS number 17378-30-2 for unambiguous identification.
  • Molecular formula C4H9Cl2O3P, molecular weight 206.99 g/mol.
  • Reported purity >95% (HPLC) from analytical standards vendors.
  • Available in small laboratory quantities suitable for research use.

ENCOMPASS_PREFERRED
84

Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 50 MG
SDP

HN37 is a potent and chemically stable antiepileptic agent candidate with an EC50 of 37 nM for KCNQ2. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In vitro, HN37 is a potent neuronal Kv7 activator with subtype selectivity similar to RTG.

  • Potent and chemically stable antiepileptic agent candidate
  • EC50 of 37 nM for KCNQ2
  • Click chemistry reagent with an Alkyne group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
  • Potent neuronal Kv7 activator with subtype selectivity similar to RTG

ENCOMPASS_PREFERRED
85

eMolecules​ Oakwood Chemical 1-Chloroethyl chloroformate 1kg 537678299 019459 0 000 50893-53-3 MFCD00000647 142 960 C3H4Cl2O2

Oakwood Chemical 1-Chloroethyl chloroformate 1kg 537678299 019459 0 000 50893-53-3 MFCD00000647 142 960 C3H4Cl2O2

ENCOMPASS_PREFERRED
86

Medchemexpress LLC 1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 56239-24-8 | 99.0% | C9H12D4ClN3O3 | 1 MG
SDP

trans-4'-Hydroxy CCNU Lomustine-d4 is a deuterium-labeled compound, primarily used as a tracer or as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules serves as a critical method for quantitation during drug development, with the potential to influence pharmacokinetic and metabolic profiles.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs.

ENCOMPASS_PREFERRED
87

Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 5 MG
SDP

2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. It is a low-molecular-weight phosphonate (C4H9Cl2O3P, MW 206.99) with CAS 17378-30-2, provided with supporting documentation; consult the certificate of analysis for recommended storage and handling.

  • Organophosphorus intermediate for organic synthesis.
  • Molecular formula C4H9Cl2O3P; molecular weight 206.99.
  • CAS number 17378-30-2 for unambiguous identification.
  • Purity greater than 95% by HPLC.
  • Available in small research quantities, such as 5 mg.
  • Supplied with certificate of analysis for storage and handling guidance.

ENCOMPASS_PREFERRED
88

Medchemexpress LLC Hydroxy-a-sanshool 10mg | 10MG
SDP

Hydroxy-a-sanshool 10mg | 10MG

ENCOMPASS_PREFERRED
89

Medchemexpress LLC Toringin | 1329-10-8 | 99.6% | 416.38 g/mol | C21H20O9 | 10 MG
SDP

Toringin is a natural bioflavonoid isolated from the bark of Docyniopsis tschonoski, supplied for research use as a white-to-yellow solid (CAS 1329-10-8). The compound is offered in small research pack sizes and is accompanied by a product data sheet and safety data sheet.

  • Natural bioflavonoid isolated from Docyniopsis tschonoski.
  • White to yellow solid suitable for analytical and biological research.
  • Reported high purity (approximately 99.6%).
  • Supplied as a 10 mg vial for small-scale experiments.
  • Documentation available: product data sheet and safety data sheet.
  • Recommended storage: powder at -20°C; in solvent, -80°C for long-term storage.

ENCOMPASS_PREFERRED
90

Medchemexpress LLC Toringin | 1329-10-8 | 5 MG
SDP

Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski. It decreases the cis-effect of expanded CTG repeats and cytotoxicity, and rescues PC12 neuronal cells when exposed to isosakuranetin. As a flavonoid, Toringin exhibits various biological activities beneficial against conditions such as cancers and coronary heart disease, and is effective in ameliorating RNA gain of function caused by expanded CTG repeats.

  • Decreases cis-effect of expanded CTG repeats
  • Decreases cytotoxicity
  • Rescues PC12 neuronal cells
  • Ameliorates RNA gain of function
  • Exhibits various biological activities
  • Beneficial against cancers and coronary heart disease

ENCOMPASS_PREFERRED